Publications
Phosphatidylserine clustering by membrane receptors trigger LC3-associated phagocytosis
Boada-Romero, E., Guy, S.C., Palacios, G., Mari, L., Poudel, S., Li, Z., Sharma, P., Green, D.R.
Biorxiv, 2023
https://www.biorxiv.org/content/10.1101/2023.09.06.556449v1Early methionine availability attenuates T cell exhaustion
Sharma, P., Guo, A., Palacios, G., Boada-Romero, E., Verbist, K., Chen. M., Haydar, D., Immadisetty, K., Mishra, A., Peng, Junmin., Babu, M.M., Glazer, E.S., Krenciute, G., Green, D.R.
Nat Immunol 26, 1384–1396 (2025)
https://www.nature.com/articles/s41590-025-02223-6cBAF complex components and MYC cooperate early in CD8+ T cell fate
Guo, A., Huang, H., Zhu, Z., Chen, M.J., Shi, H., Sharma, P., Connelly, J.P., Liedmann, S., Dhungana, Y., Li, Z., Haydar, D., Yang, M., Beere, H., Yustein, J.T., DeRenzo, C., Purett- Miller, S.M., Giedre, K., Roberts, C.W.M., Chi, H., Green, D.R.
Nature Jul;607(7917) (2022)
https://www.nature.com/articles/s41586-022-04849-0A dual role for hepatocyte-intrinsic canonical NF-κB signaling in virus control
Namineni, S., O’Connor, T., Johansen, P., Riedl, T., Shinde, P., Pandyra, A.A., Sharma, P., Ringelhan, M., Muscaweckh, A., Katharina, B., Blank, P., Kurz, S., Durantel, D., Farhat, R., Kündig, T., Stäheli, P., Neuhaus, K., Stadler, M., Protzer, U., Wohlleber, D., Holzman, B., Binder, M., Abdullah, Z., Dejardin, E., Lang, P.A., Lang, K.S., Karin, M., Luficore, J., Kalinke, U., Knolle, P., Heikenwalder, M.
J Hepatol 72(5); 960-975 (2020)
https://www.sciencedirect.com/science/article/pii/S0168827820300106Detectable Vesicular Stomatitis Virus (VSV)–Specific Humoral and Cellular Immune Responses Following VSV–Ebola Virus Vaccination in Humans
Pötsch, J.H., Dhalke, C., Zinser, M.E., Kasonta, R., Lunemann, S., Rechtien, A., Ly, M.L., Stubbe, H.C., Krähling, V., Biedenkopf, N., Eickmann, M., Fehling, S.K., Olearo, F., Strecker, T., Sharma, P., Lang, K.S., Lohse, A.W., Schmiedel, S., Becker, S., VSV-Ebola Consortium, Addo, M.M.
J Infect Dis, 219(4):556-561. (2018)
https://academic.oup.com/jid/article/219/4/556/5187947CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection
Khairnar, V., Duhan, V., Patil, A.M., Zhou, F., Bhat, H., Thoens, C., Sharma, P., Adomati, T., Friedrich, K.S., Bezgovesk, J., Dreesen, J.D., Wennemucth, G., Westendorf, A., Zelinskyy, G., Dittmer, U., Hardt, C., Timm, J., Göthert, J.R., Lang, P.A., Singer, B.B., Lang, K.S.
Nat Commun 9, 2561. (2018)
https://www.nature.com/articles/s41467-018-04832-2SGLT1 Deficiency Turns Listeria Infection into a Lethal Disease in Mice
Sharma, P., Khairnar, V., Vrhovac, I., Pandyra, A.A., Singh, Y., Köpsell, H., Sabolic, I., Lang, F., Lang, P.A., Lang, K.S.
Cell Physiol Biochem 42:1358-1365 (2017)
https://karger.com/cpb/article/42/4/1358/74222/SGLT1-Deficiency-Turns-Listeria-Infection-into-aSpatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression
Kalkavan, H., Sharma, P., Kasper, H., Helfirch, I., Pandyra, A.A., Gassa, A., Virchow, I., Flatz, L., Brandenburg, T., Namineni, S., Heikenwalder, M., Höhst, B., Knolle, P.A., Wollman, G., Laer, D., Drexler, I., Rathbun, J., Cannon, P.M., Scheu, S., Bauer, J., Chauhan, J., Häussinger, D., Willimsky, G., Löhning, M., Schadendorf, D., Brandau, S., Schuler, M., Lang, P.A., Lang, K.S.
Nat. Commun 8,14447. (2017)
https://www.nature.com/articles/ncomms14447Critical Role for Very-Long Chain Sphingolipids in Invariant Natural Killer T Cell Development and Homeostasis
Saroha, A., Pewzner-Jung, J., Ferreira, N.S., Sharma, P., Jouan, Y., Kelly, S.L., Feldmesser, E., Merrill, A.H., Trottein, F., Paget, C., Lang, K.S., Futerman, A.H.
Front Immunol. 8:1386 (2017)
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2017.01386/fullExpression of JAK3 Sensitive Na+ Coupled Glucose Carrier SGLT1 in Activated Cytotoxic T Lymphocytes
Bhavsar, S.K., Singh, Y., Sharma, P., Khairnar, V., Hosseinzadeh, Z., Zhang, S., Palmada, M., Sabolic, I., Koepsell, H., Lang, K.S., Lang, P.A., Lang, F.
Cell. Physiol. Biochem. 39, 1209–1228 (2016)
https://karger.com/cpb/article/39/3/1209/74086/Expression-of-JAK3-Sensitive-Na-Coupled-GlucoseInduction of the type I interferon response in neurological forms of Gaucher disease
Vitner, E.B., Farfel-Becker, T., Ferreira, N.S., Leshkowitz, D., Sharma, P., Lang, K.S., and Futerman, A.H.
J Neuroinflammation 13, 104. (2016)
https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-016-0570-2Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death
Pandyra, A.A., Mullen, P.J., Goard, C.A., Ericson, E., Sharma, P., Kalkat, M., Yu, R., Pong, J.T., Brown, K.R., Hart, T., Gebbia, M., Lang, K.S., Giaever, G., Nislow, C., Moffat, J., Penn, L.Z.
Oncotarget 6, 26909–26921. (2015)
https://www.oncotarget.com/article/4817/text/CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production
Khairnar, V., Duhan, V., Maney, S.K., Honke, N., Shaabani, N., Pandyra, A.A., Seifert, M., Pozdeev, V., Xu, H.C., Sharma, P., Baldin, F., Marquardsen, F., Merches, K., Lang, E., Kirschning, C., Westendorf, A.M., Häussinger, D., Lang, F., Dittmer, U., Küppers, R., Recher, M., Hardt, C., Scheffrahn, I., Beauchemin, N., Göthert, J.R., Singer, B.B., Lang, P.A., Lang, K.S.
Nat Commun 6, 6217. (2015)
https://www.nature.com/articles/ncomms7217Toso regulates differentiation and activation of inflammatory dendritic cells during persistence-prone virus infection
Lang, P.A., Meryk, A., Pandyra, A.A., Brenner, D., Brüstle, A., Xu, H.C., Merches, K., Lang, F., Khairnar, V., Sharma, P., Recher, M., Shaabani, N., Duncan, G.S., Duhan, V., Homey, B., Ohashi, P.S., Häussinger, D., Knolle, P.A., Honke, N., Mak, T.W., Lang, K.S.
Cell Death Differ. 22, 164–173. (2015)
https://www.nature.com/articles/cdd2014138Type I Interferon Protects Antiviral CD8+ T Cells from NK Cell Cytotoxicity
Xu, H., Grusdat, M., Pandyra, A., Polz, R., Huang, J., Sharma, P., Deenen, R., Köhrer, K., Rahbar, R., Diefenbach, A., Gibbert, K., Löhning, M., Höcker, L., Waibler, Z., Häussinger, D., Mak, T.W., Ohashi, P.S., Lang, K.S., Lang, P.A.
Immunity 40, 949–960. (2014)
https://www.cell.com/article/S1074-7613(14)00182-4/fulltext